I think he will go strong. We have eight games to get out of the league stage, and this is one of the more winnable ones. He will want the win.
Plus it's still early in the season, every single player will want to be playing in this match. Are you going to tell Watkins, McGinn, Ramsey, Rogers, and Konsa they're not starting their first Champions League game?
There will be plenty of opportunities to rest and rotate further on, but as Emery and the club value european competition second only to the Prem, I'm expecting few changes.