The midfield is going to be a massive problem now for the next couple of months. We haven't had a right sided attacker all season and in the centre were now cobbling together Bogarde, who isn't good enough with a football, Onana who is never fully fit and Luiz who hasn't played much football in 2 years. That midfield currently won't be good enough to finish top 5. It's a shame but Kamara, McGinn and Tielemans all out at the same time is going to kill the season.
Throw in Watkins somehow getting injured when he's always fit in a meaningless group stage game.