I'd start Gil. And I don't think you can plan on starting players and then taking them off after an hour or so, injuries to to other players can mean your subs are used early, and even if they play an hour that's an hour to get crocked. I'd definitely rest Delph, Grealish and Benteke.
GuzanLowton | Vlaar | Baker | CissokhoSanchezBacuna | Gil | RichardsonAgbonlahor | Sinclair