Libor Kozak is set to make his long awaited return from injury in tonight's U21 meeting with Wolves at Molineux.
The striker has been sidelined for 14 months after breaking his leg on the practice pitches of Bodymoor Heath in January 2014.
Loan moves for Lewis Kinsella and Graham Burke sees Niall Mason and Rory Hale come in while regulars Jerell Sellars and Riccardo Calder are back in the starting line-up.
Meanwhile, Carles Gil features in his second consecutive match for Gordon Cowans' side.
Villa U21s make the short trip to Molineux as they look to make it a hat-trick of victories over their Black Country rivals for the 2014-15 campaign.
Back in October 2014, goals from Jack Grealish and Jerell Sellars helped Villa to a 2-1 win in the reverse Barclays U21 Premier League fixture at Burton.
The two West Midlands sides also met in a Premier League Cup last 16 tie.
Michael Drennan's early goal was the difference that day.
Cowans' Young Lions are in good form ahead of the trip and have picked up maximum points in their previous two matches.
Two late strikes beat Bolton at the Macron Stadium before an experienced claret and blue XI saw off West Brom 3-0 at Bodymoor Heath last time out.
Goals from Graham Burke, Grealish and Joshua Webb secured victory over the Baggies.
Meanwhile, basement side Wolves go into the clash on the back of a 2-0 defeat at the hands of Derby last Thursday.
The division's draw specialists have struggled for consistency.
They have won one, drawn eight and lost eight of their league games.
Kick-off at Molineux is 7pm.
WOLVES U21: McCarey, Matinyadze, O'Hanlon, Evans, Hayden, Upton, Ismail, Kellermann, Wilson, Hunte, Graham. Subs: Simpson, Burgoyne, Weeks, Harris, Bancessi.
VILLA U21: Steer, Leggett, Toner (C), Mason, Hale, Calder, Cowans, Sellars, Gil, Hepburn-Murphy, Kozak. Subs: Watkins, Webb, McKirdy, Green, Suliman.